Distributions of p53 codon 72 polymorphism in primary open angle glaucoma
نویسندگان
چکیده
منابع مشابه
Association between p53 Codon 72 (Arg72Pro) Polymorphism and Primary Open-Angle Glaucoma in Iranian Patients
Background: Glaucomatous neuropathy is a type of cell death due to apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (POAG) has been studied in some ethnic groups. This study is the first association analysis of POAG and p53 codon 72 polymorphism in Iranian patients...
متن کاملCLINICAL SCIENCE Distributions of p53 codon 72 polymorphism in primary open angle glaucoma
Background: Glaucomatous neuropathy is a type of cell death by apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, p53 codon 72 polymorphism has been extensively studied to determine the risk factors responsible for many diseases. In the p53 gene, a single base change from G to C causes the alternation of amino acid residue 72 from arginine to proline. In this study t...
متن کاملDistributions of p53 codon 72 polymorphism in primary open angle glaucoma.
BACKGROUND Glaucomatous neuropathy is a type of cell death by apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, p53 codon 72 polymorphism has been extensively studied to determine the risk factors responsible for many diseases. In the p53 gene, a single base change from G to C causes the alternation of amino acid residue 72 from arginine to proline. In this study th...
متن کاملassociation between p53 codon 72 (arg72pro) polymorphism and primary open-angle glaucoma in iranian patients
background: glaucomatous neuropathy is a type of cell death due to apoptosis. the p53 gene is one of the regulatory genes of apoptosis. recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (poag) has been studied in some ethnic groups. this study is the first association analysis of poag and p53 codon 72 polymorphism in iranian patients...
متن کاملDistribution of p53 codon 72 polymorphism in Indian primary open angle glaucoma patients.
PURPOSE Glaucoma is a complex neurodegenerative disorder of the eye. Primary Open Angle Glaucoma (POAG) is the most common type, accounting for over half of the total cases. Recently, a significant difference in the distribution of the codon 72 polymorphism of the tumor suppressor gene p53 between control subjects and POAG patients of Chinese origin (p=0.00782) was demonstrated. The proline res...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2002
ISSN: 0007-1161
DOI: 10.1136/bjo.86.7.767